Scientists use a variety of high-powered microscopes to study the surface and internal structure of a sample, and to measure the size of things too tiny to see with light microscopes.
An electron microscope uses a beam of accelerated electrons as a source of illumination. A transmission electron microscope (TEM) can magnify objects or microbes up to 10,000,000x. Most light microscopes magnifies samples at up to 2,000x. A scanning electron microscope (SEM) produces a gray-scale image with depth and high clarity, which later is often colorized to illustrate different areas.
- Moreno, N., Tharp, B., Erdmann, D, Rahmati Clayton, S., and Denk, J. (2012) The Science of Microbes Teacher’s Guide. Baylor College of Medicine: Houston. ISBN: 978-1-888997-54-5
- TEM of Legionella pneumophila bacterium courtesy of the CDC/7306.
- SEM of Legionella pneumophila courtesy of the CDC/6640/Dr. Barry S. Fields.
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Grant Number: 5R25RR018605