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Author(s): Wah Chiu, PhD, and Matthew Dougherty, MS. Slides: Sonia Rahmati Clayton, PhD, and Colleen Krockenberger, BS.

Herpes Virus Type 1 - Structure

Transcript from "Viruses," National Center for Macromolecular Imaging
With the electron microscope, the four parts of the cold sore virus, herpes virus 1, are visible. When it has a chance to invade a healthy cell, the virus behaves like the Trojan horse. Its sticky outer shell of proteins, fats and sugars tricks the cell so the cell absorbs the virus. But once inside, the virus breaks apart and its genetic poison attacks the cell's nucleus. The virus's DNA reprograms the cell's DNA. The cell's new job is to make hundreds of thousands of copies of the virus. When its work is done, the cell dies.

Additional Virus information:
Triplex, Penton and Hexon all are structural units of the capsid. The capsid of the Herpes Virus type virion is an icosohedron made of 12 pentons and 150 hexons that are surrounded and connected by triplexes.

Funded by the following grant(s)

Virus images courtesy of Wah Chiu, PhD, National Center for Macromolecular Imaging at Baylor College of Medicine. Funding for the images provided by NCMI, NIH.